Ignacio Segarra;Raphael J. Mannino;Leila Zarif;Tuo Jin
发明人:
Leila Zarif,Tuo Jin,Ignacio Segarra,Raphael J. Mannino
申请号：
US13441030
公开号：
US20120294901A1
申请日:
2012.04.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A process for producing a small-sized, lipid-based cochleates. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
