METHODS FOR INHIBITING TIE2 KINASE USEFUL IN THE TREATMENT OF CANCER

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专利权人:

发明人:

申请号：

EP13896951.4

公开号：

EP3065549A1

申请日:

2013.11.07

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1Hpyrazol- 5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.

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中国工程科技知识中心

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http://www.ckcest.cn/home/