Flynn, Daniel L.,Kaufman, Michael D.,Smith, Bryan,Rudoltz, Marc S.
申请号：
AU2013404949
公开号：
AU2013404949B2
申请日:
2013.11.07
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1Hpyrazol- 5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
