FLYNN, DANIEL L.,KAUFMAN, MICHAEL D.,SMITH, BRYAN,RUDOLTZ, MARC S.
申请号：
CA2929715
公开号：
CA2929715A1
申请日:
2013.11.07
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1Hpyrazol- 5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
