Isodidiazepine [5,1-a] derivatives or salts, 2,3-dioxigenata inhibitors (IDA)； drug synthesis, an immunosuppressive tool for the treatment of infectious diseases or cancers.

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专利权人:

NEWLINK GENETICS CORPORATION

发明人:

KUMAR, SANJEEV,MAUTINO, MARIO,WALDO, JESSE,JAIPURI, FIROZ,KESHARWANI, TANAY,ZHANG, XIAOXIA,MAUTINO MARIO,KUMAR SANJEEV,WALDO JESSE,JAIPURI FIROZ,KESHARWANI TANAY,ZHANG XIAOXIA

申请号：

CL2013002990

公开号：

CL2013002990A1

申请日:

2013.10.15

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase； treating indoleamine 2,3-dioxygenase (IDO) mediated inimunosuppression； treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase； enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent； treating tumor-specific immunosuppression associated with cancer； and treating immunosuppression associated with an infectious disease.COMPUESTOS DERIVADOS DE IMIDAZO[5,1-A]ISOINDOL O SUS SALES, INHIBIDORES DE INDOLAMINA 2,3-DIOXIGENASA (IDO)； COMPOSICION FARMACEUTICA, UTILES PARA TRATAR LA INMUNOSUPRESION ASOCIADA CON UNA ENFERMEDAD INFECCIOSA O CANCER.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/