The present invention provides uses of a Solanum betaceum extract for reducing retinal damage caused by blue light. So that to effectively reduce retinal cells damage and apoptosis, hypoxic abnormal vascular angiogenesis and the occurrence of macular lesions. The Solanum betaceum extract is prepared by extracting Solanum betaceum using water, alcohols, or mixtures of water and alcohols as solvents.本發明提供一種樹番茄萃取物用於降低藍光所致視網膜損傷的用途，能有效減少照射藍光所致視網膜色素上皮細胞之凋亡、降低缺氧性之血管不正常新生，及降低視網膜黃斑部病變等相關眼疾的發生，其中該樹番茄取物係樹番茄以水、醇、或醇水混合物之溶劑所萃取而得。
