The present invention provides use of an unripe fig fruit extract for manufacture of composition for reducing skin collagen loss. The unripe fig fruit extract is prepared by extraction of unripe fig fruit using water, alcohols, or mixtures of water and alcohols as solvents. This extract not only enhances collagen production by skin fibroblasts, but also prevents loss of collagen with normal structure and function due to glycation, whereby helping to maintain youthful skin.本發明提供一種無花果幼果萃取物用於製備減少皮膚膠原蛋白損失之組合物之用途。該無花果幼果萃取物係以水、醇類、或醇水混合物為溶劑對無花果幼果進行萃取而製得，其可促進皮膚纖維母細胞生成膠原蛋白，亦能避免具有正常結構與功能的膠原蛋白因醣化反應而喪失，因此有助於維持皮膚的年輕狀態。
