GRASSO LUIGI;MURAMOTO KENZO;KAWANO TETSU;YASUAKI SAKAMOTO;SPIDELJARED;IMAI TOSHIO;NISHIMURA MIYUKI;KLINE JAMES BRADFORD;HORIZOE TATSUO
发明人:
申请号：
IL22638313
公开号：
IL226383D0
申请日:
2013.05.16
申请国别(地区):
IL
年份:
2013
代理人:
摘要：
The present invention relates to novel humanized, chimeric and murine antibodies that have binding specificity for the human CC chemokine ligand 20 (CCL20). The present invention further relates to heavy chains and light chains of said antibodies. The invention also relates to isolated nucleic acids, recombinant vectors and host cells that comprise a sequence which encodes a heavy chain and/or a light chain of said antibodies, and to a method of preparing said antibodies. The anti-CCL20 antibodies of the invention can be used in therapeutic applications to treat, for example, inflammatory and autoimmune disorders and cancer.
