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NEUTRALISIERUNG VON ANTIKÖRPERN GEGEN CCL20
专利权人:
LTD.;EISAI R&D MANAGEMENT CO.
发明人:
IMAI, TOSHIO,KLINE, BRAD,KAWANO, TETSU,GRASSO, LUIGI,SAKAMOTO, YOSHIMASA,SPIDEL, JARED,NISHIMURA, MIYUKI,MURAMOTO, KENZO,HORIZOE, TATSUO
申请号:
EP11841462
公开号:
EP2640744A4
申请日:
2011.11.18
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to novel humanized, chimeric and murine antibodies that have binding specificity for the human CC chemokine ligand 20 (CCL20). The present invention further relates to heavy chains and light chains of said antibodies. The invention also relates to isolated nucleic acids, recombinant vectors and host cells that comprise a sequence which encodes a heavy chain and/or a light chain of said antibodies, and to a method of preparing said antibodies. The anti-CCL20 antibodies of the invention can be used in therapeutic applications to treat, for example, inflammatory and autoimmune disorders and cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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