THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY
发明人:
SPIEKERKOETTER, EDDA,RABINOVITCH, MARLENE,BEACHY, PHILIP, A.,SOLOW-CORDERO, DAVID
申请号:
EP12779354
公开号:
EP2704711A4
申请日:
2012.04.30
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.