The Board of Trustees of The Leland Stanford Junior University
发明人:
Spiekerkoetter, Edda,Rabinovitch, Marlene,Beachy, Philip A.,Solow-Cordero, David
申请号:
AU2012250974
公开号:
AU2012250974B9
申请日:
2012.04.30
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.