The Board of Trustees of the Leland Stanford Junior University
发明人:
Edda SPIEKERKOETTER,Marlene RABINOVITCH,Phillip A. BEACHY,David SOLOW-CORDERO
申请号:
US15782153
公开号:
US20180185340A1
申请日:
2017.10.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method for reducing pulmonary hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.