Marlene Rabinovitch;Philip A. Beachy;Edda Spiekerkoetter;David Solow-Cordero
发明人:
Edda Spiekerkoetter,Marlene Rabinovitch,Philip A. Beachy,David Solow-Cordero
申请号:
US14113375
公开号:
US09474745B2
申请日:
2012.04.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.