THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNOR UNIVERSITY
发明人:
SPIEKERKOETTER, EDDA,RABINOVITCH, MARLENE,BEACHY, PHILIP A.,SOLOW-CORDERO, DAVID
申请号:
CA2834368
公开号:
CA2834368A1
申请日:
2012.04.30
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.