ヘスペレチン-7-β-マルトシド及びその製造方法並びにその用途

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专利权人:

株式会社林原生物化学研究所

发明人:

三宅 俊雄,湯本 隆

申请号：

JP2005222955

公开号：

JP4902151B2

申请日:

2005.08.01

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a method for producing a hesperetin-7-&beta-maltoside and to provide uses thereof.

SOLUTION: The method for producing the hesperetin-7-&beta-maltoside is characterized as follows. Hesperidin is reacted with an enzyme having an &alpha-1,6-rhamnosidase activity to remove rhamnose. The resultant 7-&beta-D-monoglucosyl hesperetin is reacted with a glycosyltransferase in the presence of starch or dextrin to add one or more &alpha-D-glucoses. A method for producing a hesperetin glycoside composition containing the hesperetin-7-&beta-maltoside is characterized as follows. The resultant addition product is reacted with a hydrolase to reduce the average number of added glucoses. Thereby, the average number of added glucoses is regulated to 1.5-3.0 based on the 7-&beta-D-monoglucosyl hesperetin. A method for improving the water solubility of a sparingly water-soluble substance comprises making the sparingly water-soluble substance selected from the hesperidin, the 7-&beta-D-monoglucosyl hesperetin, hesperetin, rutin, naringin and isoflavone coexist with the hesperetin-7-&beta-maltoside.

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