HECKROTH, Heike,NEFZGER, Hartmut,WAMPRECHT, Christian
申请号：
ES09715523
公开号：
ES2608756T3
申请日:
2009.02.17
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
Use of a polyurea system for the preparation of an agent to generate a barrier against postoperative adhesions, the polyurea system A) comprising aspartic acid esters with amine functionality of the general formula (I) ** Formula ** in which X it is an n-valent organic residue that is obtained by removing the primary amino groups from an n-functional amine, R1, R2 are the same or different organic residues that do not have active hydrogen according to Zerewitinoff and n is an integer of at least 2, and B ) isocyanate functional prepolymers having residual monomer contents of less than 1% by weight, which can be obtained by reaction of B1) aliphatic isocyanates with B2) a polyol component with average molecular weights in number>； = 400 g / mol and OH functionalities averages of 2 to 6, containing polyester polyols and / or polyester polyether polyols as well as, if necessary, polyether polyols, or C), if necessary, organic fillers that have a na viscosity measured in accordance with DIN 53019 at 23 ° C in the range of 10 to 6000 mPas and D) if necessary reaction products of isocyanate functional prepolymers according to the definition of component B) with aspartic acid esters according to component A) and / or organic fillers according to C).Uso de un sistema de poliurea para la preparación de un agente para generar una barrera contra adherencias posoperatoria, comprendiendo el sistema de poliurea A) ésteres de ácido aspártico con funcionalidad amina de la fórmula general (I)**Fórmula** en la cual X es un residuo orgánico n-valente que se obtiene retirando los grupos amino primarios de una amina n-funcional, R1, R2 son residuos orgánicos iguales o diferentes que no presentan hidrógeno activo según Zerewitinoff y n es un número entero de al menos 2, y B) prepolímeros con funcionalidad isocianato que tienen contenidos residuales de monómero de menos del 1 % en peso, que pueden obtenerse mediante reacción de B1) isocianatos alifáticos con B2) un componente poliol con
