LUTZ, Christian,SIMON, Werner,WERNER-SIMON, Susanne,MÜLLER, Christoph,HECHLER, Thorsten,KULKE, Michael
申请号：
SG11201912224P
公开号：
SG11201912224PA
申请日:
2018.08.06
申请国别(地区):
SG
年份:
2020
代理人:
摘要：
The invention relates to novel methods for synthesizing amanitin derivatives having a hydroxy group attached to the central tryptophan moiety. The invention furthermore relates to novel amanitin derivatives having a hydroxy group attached to position 4′, 5′ or 7′ of the central tryptophan moiety, novel conjugates of such amanitin derivatives, and pharmaceutical compositions comprising such conjugates.
