Christian Lutz,Werner Simon,Susanne Werner-Simon,Christoph Müller,Torsten Hechler,Michael Kulke
申请号：
US16637376
公开号：
US20200181200A1
申请日:
2018.08.06
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to novel methods for synthesizing amanitin derivatives having a hydroxy group attached to the central tryptophan moiety. The invention furthermore relates to novel amanitin derivatives having a hydroxy group attached to position 4′；, 5′； or 7′； of the central tryptophan moiety, novel conjugates of such amanitin derivatives, and pharmaceutical compositions comprising such conjugates.
