Lutz, Christian,Simon, Werner,Werner-Simon, Susanne,Müller, Christoph,Hechler, Thorsten,Kulke, Michael
申请号:
AU2018314668
公开号:
AU2018314668A1
申请日:
2018.08.06
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The invention relates to novel methods for synthesizing amanitin derivatives having a hydroxy group attached to the central tryptophan moiety. The invention furthermore relates to novel amanitin derivatives having a hydroxy group attached to position 4', 5' or 7' of the central tryptophan moiety, novel conjugates of such amanitin derivatives, and pharmaceutical compositions comprising such conjugates.