NOUVEAU PROCEDE DE SYNTHESE D'AMANITINES

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专利权人:

HEIDELBERG PHARMA RESEARCH GMBH

发明人:

LUTZ, CHRISTIAN,SIMON, WERNER,WERNER-SIMON, SUSANNE,MULLER, CHRISTOPH,HECHLER, TORSTEN,KULKE, MICHAEL,HECHLER, THORSTEN

申请号：

CA3066867

公开号：

CA3066867A1

申请日:

2018.08.06

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The invention relates to novel methods for synthesizing amanitin derivativeshaving a hydroxy group attached to thecentral tryptophan moiety. The invention furthermore relates to novel amanitinderivatives having a hydroxy group attached to position4', 5' or 7' of the central tryptophan moiety, novel conjugates of suchamanitin derivatives, and pharmaceutical compositions comprisingsuch conjugates.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/