Compounds and compositions as channel activating protease inhibitors

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专利权人:

Zhiwei Wang;David C. Tully;Arnab K. Chatterjee

发明人:

David C. Tully,Arnab K. Chatterjee,Zhiwei Wang

申请号：

US12526029

公开号：

US08293915B2

申请日:

2008.01.07

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.

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中国工程科技知识中心

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http://www.ckcest.cn/home/