DAVID C. TULLY,ARNAB K. CHATTERJEE,AGNES VIDAL,BADRY BURSULAYA
申请号：
BRPI0806970
公开号：
BRPI0806970A2
申请日:
2008.01.04
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating chan-nel activating proteases, and methods for using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSSI1E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.
