COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATION PROTEASE INHIBITORS.

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专利权人:

IRM LLC

发明人:

DAVID C. TULLY,ARNAB K. CHATTERJEE,AGNES VIDAL,BADRY BURSULAYA,GLEN SPRAGGON

申请号：

BRPI0720799

公开号：

BRPI0720799A2

申请日:

2007.11.21

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 ( e.g ., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/