WAKENHUT FLORIAN,UNDERWOOD TOBY JAMES,GIBSON KARL RICHARD,GREEN MARTIN PETER
申请号：
TN2011000131
公开号：
TN2011000131A1
申请日:
2011.03.14
申请国别(地区):
TN
年份:
2012
代理人:
摘要：
a compound of formula (i) or its pharmaceutically acceptable salts or derivatives of formula (i), solvation in which r1 and r2 are each independently h, an alkyl group halog\u00e8no, cf3, c1 to c3 and c1 to c3 alkoxy in r3 represents an alkyl group, cycloa c1 to c6. lkyle c3 through c6.phenyl, optionally substituted with one or more substituents selected from each independament substituents (optionally substituted (ra) or with one or more substituents - oxo and c1 to c4 alkyl, r4 is h or an alkyl group of c1 to c3.r5 is an alkyl group, optionally substituted c1 to c6 substituents with one or more substituents selected from each independament rb).cycloalkyl optionally substituted c3 to c6 (with one or more substituents selected from the independament substituantsoxo and optionally substituted with oh or het2 (with one or more substituents each independently selected from the substituents r, an atom of oxygen and one atom (e), or (c) the sulphur atom of oxygen or sulfur atom, optionally substituted with one or a number ofeach selected independently from a substituent or substituents - oxo alkyl, c1 to c4 alkyl group and r6 represents a c1 to c3 (optionally substituted with one or more substituents selected from the substituents may r (f), (facultat in c3 to c5 cycloalkyl a comprehensive halogeno substituted with one or more substituents) or halogeno cn.rf is a group or halogen or carrying no phenyl, and processes for the preparation of compositions and uses thereof, for example in the treatment of the uterins endometriose or fibroids.un composé de formule (I), ou un de ses sels ou produits de solvatation pharmaceutiquement acceptables formule (I) dans laquelle, R1 et R2 représentent chacun indépendamment H, un groupe halogèno, CF3, alkyle en C1 à C3 ou alkoxy en C1 à C3 R3 représente un groupe alkyle en C1 à C6, cycloalkyle en C3 à C6, phényle (facultativement substitué avec un ou plusieurs substituants choisis chacun independament parmi des substituants Ra ) ou HET(
