Provided is a uracil compound or a salt thereof,which has potent human dUTPase inhibitory activity and isuseful as, for example, an antitumor drug.A uracil compound represented by the general formula(I) or a salt thereof:(see formula I)wherein n represents an integer of 1 to 3； X represents abond, an oxygen atom, a sulfur atom, or the like； Yrepresents a linear or branched alkylene group having 1 to8 carbon atoms, or the like； and Z represents -SO2NR1R2 or-NR3SO2-R4, wherein R1 and R2 each represent an alkyl grouphaving 1 to 6 carbon atoms, an aralkyl group which isoptionally substituted, or the like； R3 represents analkyl group having 1 to 6 carbon atoms, or the like； andR4 represents an aromatic hydrocarbon group, anunsaturated heterocyclic group, or the like.
