HÉTÉROATOME CONTENANT DES INHIBITEURS DE LA DÉSOXYURIDINE TRIPHOSPHATASE

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专利权人:

University Of Southern California

发明人:

申请号：

EP15733304.8

公开号：

EP3089964A4

申请日:

2015.01.02

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions in a method of treating cancer. The dUTPase inhibitors disclosed contain a uracil isostere in the molecule represented by a 2,6-diketopiperazine moiety. Thioanalogs of the uracil isostere where a thione replaces each of the ketone are also disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/