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NOUVEAU DÉRIVÉ DE L'ACIDE CARBOXYLIQUE DE PYRIDONE OU SON SEL CORRESPONDANT
专利权人:
Ltd.;Wakunaga Pharmaceutical Co.
发明人:
申请号:
EP18770988.6
公开号:
EP3604305A1
申请日:
2018.03.23
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
It is intended to provide a novel compound having high antitumor activity and low toxicity to normal cells. The present invention provides a pyridone carboxylic acid derivative represented by the following formula (1) or a salt thereof wherein R1 represents a hydrogen atom, a halogen atom or the like; R2 represents a hydrogen atom, a halogen atom or the like; R3 to R6 each represent a hydrogen atom or the like; R7 represents a hydrogen atom or the like; R8 represents a hydrogen atom, a halogen atom, the following formula (a) (wherein Ra1 and Ra2 each represent a hydrogen atom, a hydroxy group, an optionally substituted lower alkyl group or the like) or the like, or R7 and R8 together represent =N-OR10 (wherein R10 represents a hydrogen atom, an optionally substituted lower alkyl group, or an aralkyl group), or R7 and R8 form an optionally substituted 4- to 6-membered saturated hetero ring together with the adjacent carbon atom, or the like; R9 represents a hydrogen atom or the like; X represents a nitrogen atom or the like; and Y represents a nitrogen atom or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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