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NOUVEAU DERIVE DE L'ACIDE CARBOXYLIQUE DE PYRIDONE OU SON SEL CORRESPONDANT
专利权人:
LTD.;WAKUNAGA PHARMACEUTICAL CO.
发明人:
YAMAGUCHI, TOMONORI,ITOH, KENJI,HIRANO, TATSUYA,SHIMABARA, RUMIKO,KAWAKUBO, YOHEI,SATO, MASAYUKI,YAMASHITA, JUNPEI,YAZAKI, AKIRA,UESHIMA, TAICHI
申请号:
CA3061877
公开号:
CA3061877A1
申请日:
2018.03.23
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
It is intended to provide a novel compound havinghigh antitumor activity and low toxicity to normal cells.The present invention provides a pyridone carboxylic acidderivative represented by the following formula (1) or asalt thereof wherein R1 represents a hydrogen atom, ahalogen atom or the like; R2 represents a hydrogen atom,a halogen atom or the like; R3 to R6 each represent ahydrogen atom or the like; R7 represents a hydrogen atomor the like; R8 represents a hydrogen atom, a halogenatom, the following formula (a) (wherein Ra1 and Ra2 eachrepresent a hydrogen atom, a hydroxy group, an optionallysubstituted lower alkyl group or the like) or the like,or R7 and R8 together represent =N-OR10 (wherein R10represents a hydrogen atom, an optionally substitutedlower alkyl group, or an aralkyl group), or R7 and R8form an optionally substituted 4- to 6-membered saturatedhetero ring together with the adjacent carbon atom, orthe like; R9 represents a hydrogen atom or the like; Xrepresents a nitrogen atom or the like; and Y representsa nitrogen atom or the like.
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中国工程科技知识中心
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