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FGF RECEPTOR-ACTIVATING N-ACYL OCTASACCHARIDES,PREPARATION THEREOF,AND THERAPEUTIC USE THEREOF
专利权人:
SANOFI
发明人:
DRIGUEZ PIERRE ALEXANDRE,DUCHAUSSOY PHILIPPE,FONS PIERRE,HERBERT CORENTIN,LASSALLE GILBERT
申请号:
ZA201201028
公开号:
ZA201201028B
申请日:
2012.02.13
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
The invention relates to FGF receptor-activating N-acyl octasaccharides having Formula (I), wherein: R1 is an O-alkyl group optionally replaced by one or more aryl or cycloalkyl groups, R2 is an OSO3− or hydroxyl group, R3 is an alkyl, cycloalkyl, or alkyl-cycloalkyl group, R4 is a disaccharide having Formula (II), R6 is a disaccharide having Formula (III), and R8 is a disaccharide having Formula (IV), where R5, R7, and R9 are OSO3− or hydroxyl groups. The invention further relates to the preparation of said octasaccharides and to the therapeutic use thereof.
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中国工程科技知识中心
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