KIM, DAE KEE,SHEEN, YHUN YHONG,JIN, CHENG HUA,PARK, CHUL-YONG,SREENU, DOMALAPALLY,RAO, KOTA SUDHAKAR,KRISHNAIAH, MADDEBOINA,SUBRAHMANYAM, VURA BALA
申请号:
CA2803577
公开号:
CA2803577C
申请日:
2011.06.24
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
This invention relates to 2-pyridyl substituted imidazoles which are inhibitors of the transforming growth factor-ß (TGF-ß) type I receptor (ALK5) and/or the activin type I receptor (ALK4), methods for their preparation, and their use in medicine, specifically in the treatment and prevention of a disease state mediated by these receptors.