IMIDAZOLES SUBSTITUÍDOS COM 2-PIRIDILO COMO INIBIDORES ALK5 E/OU ALK4 TERAPÊUTICOS

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专利权人:

EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION

发明人:

DAE KEE KIM,YHUN YHONG SHEEN,CHENG HUA JIN,CHUL-YONG PARK,DOMALAPALLY SREENU,KOTA SUDHAKAR RAO,MADDEBOINA KRISHNAIAH,VURA BALA SUBRAHMANYAM

申请号：

PT11801087

公开号：

PT2588479E

申请日:

2011.06.24

申请国别(地区):

PT

年份:

2015

代理人:

摘要：

This invention relates to 2-pyridyl substituted imidazoles (I) which are inhibitors of the transforming growth factor-² (TGF-²) type I receptor (ALK5) and/or the activin type I receptor (ALK4), methods for their preparation, and their use in medicine, specifically in the treatment and prevention of a disease state mediated by these receptors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/