DUCHAUSSOY, PHILIPPE,FONS, PIERRE,HERBERT, CORENTIN,LASSALLE, GILBERT,DRIGUEZ, PIERRE ALEXANDRE
申请号：
SG2012010203
公开号：
SG178405A1
申请日:
2010.08.12
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
The invention relates to FGF receptor-activating N-acyl octasaccharides having Formula (I), wherein: R1 is an O-alkyl group optionally replaced by one or more aryl or cycloalkyl groups, R2 is an OSO3- or hydroxyl group, R3 is an alkyl, cycloalkyl, or alky-cycloalkyl group, R4 is a disaccharide having Formula (II), R6 is a disaccharide having Formula (III), and R8 is a disaccharide having Formula (IV), where R5, R7, and R9 have OSO3 or hydroxyl groups. The invention further relates to the preparation of said octasaccharides and to the therapeutic use thereof.
