Pierre FONS;Gilbert LASSALLE;Pierre Alexandre DRIGUEZ;Philippe DUCHAUSSOY;Corentin HERBERT
发明人:
Pierre Alexandre DRIGUEZ,Philippe DUCHAUSSOY,Pierre FONS,Corentin HERBERT,Gilbert LASSALLE
申请号：
US13369675
公开号：
US20120214754A1
申请日:
2012.02.09
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to FGF receptor-activating N-acyl octasaccharides having Formula (I), wherein: R1 is an O-alkyl group optionally replaced by one or more aryl or cycloalkyl groups, R2 is an OSO3− or hydroxyl group, R3 is an alkyl, cycloalkyl, or alkyl-cycloalkyl group, R4 is a disaccharide having Formula (II), R6 is a disaccharide having Formula (III), and R8 is a disaccharide having Formula (IV), where R5, R7, and R9 are OSO3− or hydroxyl groups. The invention further relates to the preparation of said octasaccharides and to the therapeutic use thereof.
