SUI XIONG CAI,YE EDWARD TIAN,HAIJUN DONG,QINGBING XU,LIZHEN WU,LIJUN LIU,YANGZHEN JIANG,QINGLI BAO,GUOXIANG WANG,FENG YIN,CHENGYUN GU,XIUHUA HU,XIAOZHU WANG,SISHUN KANG,SHENGZHI CHEN
申请号:
PT12765230
公开号:
PT2709990T
申请日:
2012.03.31
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
Disclosed are 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones thereof, represented by the Formula (I) wherein Ar, R1-R6 are defined herein. Compounds having Formula (I) are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity.