CAI Sui Xiong,TIAN Ye Edward,DONG Haijun,XU Qingbing,WU Lizhen,LIU Lijun,JIANG Yangzhen,BAO Qingli,WANG Guoxiang,YIN Feng,GU Chengyun,HU Xiuhua,WANG Xiaozhu,KANG Sishun,CHEN Shengzhi
申请号:
SI201231630
公开号:
SI2709990T1
申请日:
2012.03.31
申请国别(地区):
SI
年份:
2019
代理人:
摘要:
Disclosed are 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones thereof, represented by the Formula (I) wherein Ar, R1-R6 are defined herein. Compounds having Formula (I) are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity.