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DERIVATI 1-((3-((1-PIPERAZINIL)KARBONIL)FENIL)METIL)-2,4(1H,3H)-HINAZOLINDIONA KAO INHIBITORI PARP ZA LEČENJE KANCERA
专利权人:
IMPACT THERAPEUTICS; INC.
发明人:
CAI, SUI XIONG,TIAN, YE, EDWARD,DONG, HAIJUN,XU, QINGBING,WU, LIZHEN,LIU, LIJUN,JIANG, YANGZHEN,BAO, QINGLI,WANG, GUOXIANG,YIN, FENG,GU, CHENGYUN,HU, XIUHUA,WANG, XIAOZHU,KANG, SISHUN,CHEN, SHENGZHI
申请号:
RSP20190877
公开号:
RS59091B1
申请日:
2012.03.31
申请国别(地区):
RS
年份:
2019
代理人:
摘要:
Disclosed are 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones thereof, represented by the Formula (I) wherein Ar, R1-R6 are defined herein. Compounds having Formula (I) are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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