Buschmann, Helmut Heinrich,Sola Carandell, Lluis,Benet Buchholz, Jordi,Cerón Bertran, Jordi Carles,Plata Salaman, Carlos Ramon,Tesson, Nicolas,CerĂłn Bertran, Jordi Carles,P
申请号：
HRP20161526
公开号：
HRP20161526T1
申请日:
2016.11.18
申请国别(地区):
HR
年份:
2016
代理人:
摘要：
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. In a preferred embodiment, co-crystals of (-)tramadol-(S)-naproxen (1:2) and (+)tramadol-(R)-naproxen (1:2) are prepared.
