BUSCHMANN Helmut Heinrich,SOL CARANDELL Lluis,BENET BUCHHOLZ Jordi,CERON BERTRAN Jordi Carles,PLATA SALAMAN Carlos Ramon,TESSON Nicolas,PLATA SALAMA
申请号：
SI200931565
公开号：
SI2349238T1
申请日:
2009.10.16
申请国别(地区):
SI
年份:
2017
代理人:
摘要：
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. In a preferred embodiment, co-crystals of (-)tramadol-(S)-naproxen (1:2) and (+)tramadol-(R)-naproxen (1:2) are prepared.
