BUSCHMANN HELMUT HEINRICH,SOLÀ CARANDELL LLUIS,BENET BUCHHOLZ JORDI,CERÓN BERTRAN JORDI CARLES,PLATA SALAMAN CARLOS RAMON,TESSON NICOLAS,PLATA SALA
申请号：
PL09736862
公开号：
PL2349238T3
申请日:
2009.10.16
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. In a preferred embodiment, co-crystals of (-)tramadol-(S)-naproxen (1:2) and (+)tramadol-(R)-naproxen (1:2) are prepared.
