BENET BUCHHOLZ, Jordi,BUSCHMANN, Helmut, Heinrich,Bertran, Jordi Carles Ceron,Plata Salaman, Carlos Ramon,SOLÿ CARANDELL, Lluis,Tesson, Nicolas
申请号:
DK09736862
公开号:
DK2349238T3
申请日:
2009.10.16
申请国别(地区):
DK
年份:
2016
代理人:
摘要:
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain. In a preferred embodiment, co-crystals of (-)tramadol-(S)-naproxen (1:2) and (+)tramadol-(R)-naproxen (1:2) are prepared.