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Immunogenic composition comprising antigenic S. aureus proteins
专利权人:
GlaxoSmithKline Biologicals S.A.
发明人:
Castado, Cindy,Germain, Sophie Marie Jeanne Valentine,Gilbert, Melanie
申请号:
AU2010280740
公开号:
AU2010280740A1
申请日:
2010.08.03
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present application relates to an immunogenic composition comprising a fragment of a staphylococcal lsd protein such as IsdA, IsdB, IsdC or IsdH which comprises a NEAT domain. Fusion proteins comprising a NEAT domain of a first staphylococcal lsd protein and a NEAT domain from a second lsd protein are also disclosed as well as fusion proteins comprising a NEAT domain of a staphylococcal lsd protein involved in an iron/heme uptake system and a ligand binding domain of a staphylococcal extracellular component binding protein, for example CIfA, CIfB, SdrC, SdrD or SdrE.
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