CASTADO CINDY,GERMAN SOPHIE MARIE JEANNE VALENTINE,GILBERT MELANIE
申请号:
IN503/KOLNP/2012
公开号:
IN2012KN00503A
申请日:
2012.03.05
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present application relates to an immunogenic composition comprising a fragment of a staphylococcal lsd pro-tein such as IsdA, LsdB, IsdC or IsdH which comprises a NEAT domain. Fusion proteins comprising a NEAT domain of a first staphylococcal lsd protein and a NEAT domain from a second lsd protein are also disclosed as well as fusion proteins comprising a NEAT domain of a staphylococcal lsd protein involved in an iron/heme uptake system and a ligand binding domain of a staphy-lococcal extracellular component binding protein, for example ClfA, CIfB, SdrC, SdrD or SdrE.