Bao Zhong Cai;Ming Zhou;Gunnar J. Hanson;Dwight D. Weller;Charles Rudolph
发明人:
Gunnar J. Hanson,Charles Rudolph,Bao Zhong Cai,Ming Zhou,Dwight D. Weller
申请号：
US13118298
公开号：
US08779128B2
申请日:
2011.05.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
