Gunnar J. Hanson,Alexander Charles Rudolph,Bao Zhong Cai,Ming Zhou,Dwight D. Weller
申请号:
US14298655
公开号:
US09469664B2
申请日:
2014.06.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Oligonucleotide analogs comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.