Gunnar J. Hanson,Alexander Charles Rudolph,Bao Zhong Cai,Ming Zhou,Dwight D. Weller
申请号：
US15247584
公开号：
US10202602B2
申请日:
2016.08.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Oligonucleotide analogs comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.
