The present invention relates to a decontamination device of the type comprising a compressor (1) supplying pressurized gas, with interposition of means of pressure regulation, means (5) suited for misting a decontamination product in the form of fine droplets in a room to be treated. This device is characterized in that the compressor (1) directly supplies the means of misting (5) at a desired pressure for use, and without interposition of a buffer tank, where the means of pressure regulation (11) are constituted by a controlled flow rate leak between the outlet (S) of the compressor (1) and the inlet (E) of the means of misting (5).本発明は、圧力調節手段が備わった加圧気体供給用のコンプレッサ(1)と、処理される室内に微小滴形態の汚染除去製品を噴霧する手段(5)と、を備えた汚染除去装置に関する。本装置は、コンプレッサ(1)が、バッファ槽を備えずに、所望の作動圧力で噴霧手段(5)に直接供給し、圧力調節手段(11)が、コンプレッサ(1)の出口(S)と噴霧手段(5)の入口(E)との間で制御された流速漏洩を含む、ことを特徴とする。