The invention mainly relates to an apparatus for decontaminating an indoor space (1), said apparatus comprising a means for spreading a liquid treatment material starting with fogging of a predetermined amount (Q) of said treatment liquid in the space (V) of the latter. The decontamination apparatus of the invention is characterized in that it comprises a means for controlling the spreading means, said controlling means being capable of stopping and resuming the fogging of said liquid material a plurality of times during a single treatment cycle. The present invention also relates to a decontamination method implementing said apparatus.