Cindy Castado,Sophie Marie Jeanne Valentine Germain,Melanie Gilbert
申请号：
US13388757
公开号：
US20120141523A1
申请日:
2010.08.03
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present application relates to an immunogenic composition comprising a fragment of a staphylococcal Isd protein such as IsdA, IsdB, IsdC or IsdH which comprises a NEAT domain. Fusion proteins comprising a NEAT domain of a first staphylococcal Isd protein and a NEAT domain from a second Isd protein are also disclosed as well as fusion proteins comprising a NEAT domain of a staphylococcal Isd protein involved in an iron/heme uptake system and a ligand binding domain of a staphylococcal extracellular component binding protein, for example ClfA, ClfB, SdrC, SdrD or SdrE.
