Jakobsen, Bent Karsten,Andersen, Bent Torben,Molloy, Peter Eamon,Li, Yi,Boulter, Jonathan Michael
申请号：
AU2010202953
公开号：
AU2010202953B2
申请日:
2010.07.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2010202953B220121004.pdf#####C -NRPonbrDCC DYS 30)57599_I DOC-12A)712U110 ABSTRACT A proteinaceous particle, for example a bacteriophage, ribosome or cell, displaying on its surface a T-cell receptor (TCR). The displayed TCR is preferably a heterodimer having a non-native disulfide bond between constant domain residues. Such display particles may be used for the creation of diverse TCR libraries for the identificaton of high affinity TCRs. Several high affinities are disclosed.
