A method for producing a hop extract, said method comprising a step for filtering a hop-containing water at 50 DEG C or higher to give a hop extract. By the production method according to the present invention, a hop extract having a high polyphenol concentration can be easily prepared. The hop extract thus produced is appropriately usable as a starting material for agents for neutralizing protein toxins, inhibiting decalcification of dental enamel, controlling body fat, protecting periodontal membrane, inactivating viruses or inhibiting overexpression of thymic stromal lymphopoietin, a symbiotic regenerative agent, an anti-inflammatory agent and compositions for treating and/or ameliorating inflammatory bowel diseases, coronary artery diseases, obesity, hyperuricemia, allergic diseases, digestive diseases, etc.本發明為一種啤酒花萃取液之製造方法,其係包含將50℃以上之含有啤酒花的水過濾,而得到啤酒花萃取液的步驟。本發明之製造方法可簡便地調製出多酚濃度高的啤酒花萃取液,適合使用作為中和蛋白質毒素、抑制琺瑯質脫鈣、調整體脂肪、保護牙根膜、病毒去活化、抑制胸腺間質性淋巴球新生因子過度表現、共生再生、抗發炎、發炎性腸疾病、冠狀動脈疾病、肥胖症、高尿酸血症、過敏疾病、消化器官疾病等的治療及/或改善用組成物的原料。